Only one other case of desmoplastic ameloblastoma has been reported in the ramus region of mandible of the 90 cases that we have reviewed. Review of. Abstract Desmoplastic Ameloblastoma is a rare histological variant of Ameloblastoma. Approximately cases of desmoplastic Ameloblastoma have been. The desmoplastic ameloblastoma (DA) is characterized by specific clinical, Article· Literature Review (PDF Available) in Oral Oncology.

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Computed tomography was performed in 20 cases usually detecting ill-defined, mixed radioluceny—radiopacity with buccal expansion Fig. The specimens showed few irregular epithelial dexmoplastic in a densely fibrous connective stroma. Radiographs revealed the presence of irregular radiolucencies with faint radio-opacities in the periapical region of 22 and A painless swelling or bony expansion are the most conspicuous clinical manifestation in most cases [ 2 — 5 ].

Case Reports in Pathology

Resection and enucleation are the main treatment modalities of DAs. Biological profile based amelobkastoma cases from the literature and own files. Formation of metaplastic bone trabeculae osteoplasia rimmed by active osteoblasts has amelkblastoma described in a few cases. Histologically, the odontogenic epithelium of DA forms irregular, stellate, or follicular islands and cords, and the centers of such lesions often appear hypercellular and contain spindle-shaped or squamous cells [ 2 ].

J Oral Maxillofac Surg. The relative frequency of hybrid lesions was reported to be 4. This article has been cited by other articles in PMC. Reconstruction with free fibula flap Cervelli, D. Radiologic features of desmoplastic variant of ameloblastoma.

Distribution of tooth involvement among 61 desmoplastic ameloblastomas B. Abstract Desmoplastic ameloblastoma DA is a relatively rare histological variant of ameloblastoma with specific clinical, radiological, and histological features. Ameloblastomas are common benign neoplasms that frequently arise in the molar and ramus regions of the mandible. DA exhibiting granular cell transformation in some of the tumor cells has been reported.


Desmoplastic ameloblastoma. A case report and literature review — Johns Hopkins University

Desmoplastic variant of ameloblastoma: A panoramic radiograph showing a well-defined large radiolucent lesion in the right mandible. Literature Review A literature review revealed 34 cases of hybrid ameloblastoma according to database of PubMed Table 1. An image of the oral cavity obtained during the initial examination showing a painless mass in the lower right premolar region. Patient was observed to be unable to appose his lips due to the size of the mass.

The accurate diagnosis of desmpolastic DA is hard to achieve before the operation; Second, DA frequently present with ill-defined border making it difficult to investigate the exact interface of the lesion with normal bone; third, the more common location in the maxilla may produce an early invasion of adjacent structures.

Ameloblastom no difference between genders has been reported 14 in the onset of this disease, desmoplaxtic in the 4th and 5th decade are most commonly affected. World Health Organization histological classification of tumors. A case report and literature review.

Based on the histological diagnosis, extraction of the lateral incisor, canine, and first premolar was performed under general anesthesia, followed by the enucleation and curettage of the lesion without cutting the inferior alveolar nerve. This case report focuses on a DA which occurred in the mandible of a 26 year-old female.

Maeloblastoma of data on 35 compiled cases of hybrid ameloblastoma. Abstract Desmoplastic Ameloblastoma is a rare histological variant of Ameloblastoma. A radical approach to its treatment is recommended as in a case of conventional ameloblastoma.


Ameloblastomaa, there is no statistically significant gender distribution as in other types of ameloblastomas. The maxillary sinus was involved in nine and the ramus in two cases. Hybrid lesions in which histopathologically conventional ameloblastoma coexists with areas of DA are rare. Data sesmoplastic different geographical regions seem to suggest a biogeographical pattern in that the desmoplastci frequency of DA is slightly higher in Asian population.

Extensive desmoplasia was seen throughout the stroma compressing the epithelial islands [ Figure 3 ]. A histopathological examination showed a hybrid ameloblastoma with a pronounced desmoplastic pattern and follicular changes.

Metaplastic bone formation has been reported in few cases. Criteria for inclusion in the here presented study were a confirmed histopathological diagnosis of DAs with a detailed clinicoradiographic description.

However, Escande et al. Desmoplastic Ameloblastoma, fibro-osseous lesion.

Desmoplastic ameloblastoma – A review.

National Center for Biotechnology InformationU. Most cases of DA were treated by resection DA occurs in the anterior or premolar regions of the jaws and there is not any difference in prevalence between the maxilla and mandible.

The remaining five remained unknown. Histologically, scattered epithelial nests and extensively desmoplasia were prominent features of DA. Desmoplastic ameloblastoma featuring basal cell ameloblastoma: The incidence of DA among ameloblastomas ranges from 0.

Giant neglected desmoplastic ameloblastoma: Tooth displacement which occurred in the present case is a common feature of DA. Materials and Methods 2. Recurrent desmoplastic ameloblastoma of the maxilla: A unique case of desmoplastic ameloblastoma of the mandible: