¿Qué debe preguntar a su médico sobre la leucemia linfocítica aguda? Es importante sostener diálogos sinceros y honestos con su médico. Existen cuatro tipos principales de leucemia: Leucemia linfoblástica (linfocítica) aguda (ALL, por sus siglas en inglés). Leucemia mieloide (mielógena) aguda. Sin embargo, el aspecto cumbre de su estudio fue el descubrimiento, hace 30 años, de que la variedad más común en el niño, la leucemia linfocítica aguda.
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Cytogenetic analysis of blast cells in childhood acute lymphoblastic leukemia has led to the recognition of specific non-random chromosomal abnormalities with prognostic value.
Most patients with ALL show karyotype abnormalities, either in chromosome number ploidy or as structural changes such as translocations, inversions, or deletions. Many of these chromosomal alterations are associated with specific cytomorphological and immunological types.
The greatest impact on patient management has been the finding that linfociticz cytogenetic result is an independent prognostic indicator.
Certain karyotypes are associated with a favorable prognosis while others indicate a poor outcome. This has led to the administration of alternative therapies according to risk. This study focuses on the most important chromosomal abnormalities found in childhood ALL and their prognostic and therapeutic implications. Cytogenetic abnormalities in acute lymphoblastic leukemia. Hospital 12 de Octubre Edificio Materno-Infantil. Hospital 12 de Octubre. This study focuses on the most important chromosomal abnormalities found in childhood ALL and their prognostic and therapeutic implications.
Current status of cytogenetic research in childhood acute lymphoblastic leukemia. Blood, 81pp. N Engl J Med,pp.
Trisomy of leukemic cell chromosomes 4 and 10 identifies children with B-progenitor cell acute lymphoblastic leukemia with a very low risk of treatment failure. Blood, 79pp. Hyperdiploid acute lymphoblastic leukemia in children. Blood, 75pp.
Cytogenetic abnormalities in childhood acute lymphoblastic leukemia correlates with clinical features and treatmentoutcome. Leukemia and Lymphoma, 7pp. Prognostic implications of chromosomal findings in lifnocitica lymphoblastic leukemia at diagnosis.
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Human acute leukemia cell line with the t 4;11 chromosomal rearrangement exhibits B lineage and monocytic characteristics. Blood, 65pp. Unifirm approch to risk classification and treatment assignment to children with acute lymphoblastic leukemia. J Clin Oncol, 14pp. Immunologic, cytogenetic, and clinical characterization of childhood acute lymphoblastic leukemia with the t 1;9 q23;p13 or its derivative.
J Clin Oncol, 12pp. Fusion with EA2 converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the 1; Mol Cell Biol, 14pp.
Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t 1;19 q23,p Blood, 8pp. Chromosomal translocations involving the E2A gene in acute lymphoblastic leukemia: Blood, 87pp. Br J Haematol, 43pp. High survival rate in advanced-stage-B-cell lymphomas and leukemias without CNS involvement with a short intensive polychemotherapy: J Clin Oncol, 9pp.
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Cancer, 40pp. Abnormalities of the long arm of chromosome 6 in childhood acute lymphoblastic leukemia. Large-scale molecular mapping of human c-myb: Oncogene, 7pp. Localization the estrogen receptor locus ESR to chromosome 6q Genomics, 17pp. Nonrandom abnormalities of chromosome 9p in childhood acute lymphoblastic leukemia: Blood, 74pp.
Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization.
Blood, 84pp. Nonrandom involvement of the 12p12 breakpoint in chromosome abnormalities of childhood acute lymphoblastic leukemia.
Blood, 68pp. Translocation 12;22 p13;q11 in myeloproliferative disorders results in fusion of the ETS-like Tel gene on 12p13 to the MN1 gene on 22q Oncogene, 10pp. Br J Haematol, 90pp.
Genes Chromosom Cancer, 9pp. Si continua navegando, consideramos que acepta su uso. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior.
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